NGF and B-cell chronic lymphocytic leukemia: Finally, pathway analysis revealed changes in lipid and lipoprotein metabolism, Fc gamma and epsilon receptor signaling, as well as NGF, VEGF, WNT, NOTCH and B-cell signaling and DNA damage response pathways (Additional file 2: Tables S9 and S10), all of which are known to be perturbed CLL [57–62].