We found that knock-down of FOXP3 in Hep3B and 97H cells led to obviously enhanced tumor proliferation (*P < 0.05, **P < 0.01; Fig. 3a) and cell migration (P = 0.009 and P = 0.002 for Hep3B and 97H, respectively; Fig. 3b) compared to control cells in vitro. Here, FOXP3 is linked to neoplasm.