Interestingly, secretome of human bone marrow mesenchymal stem cells can simultaneously decrease the levels of EIF4E and EIF4G1 and attenuate the invasiveness of NSCLC cells [23], which further supports the notion that EIF4E/G1 likely play important roles in NSCLC metastasis. This evidence concerns the gene EIF4G1 and non-small cell lung carcinoma.