Poor prognosis also was found in NSCLC with YB-1 overexpression under univariate analyses (pooled HR = 1.50, 95% CI [1.09, 2.07], P = 0.013) and multivariate analyses (pooled HR = 1.69, 95% CI [1.22, 2.35], P = 0.002). The gene discussed is YBX1; the disease is non-small cell lung carcinoma.