AKT1 and pancreatic neoplasm: In nude mice, resveratrol inhibits orthotopic pancreatic tumors by PI3K/AKT pathway [3], capsaicin suppresses pancreatic tumor xenografts by JNK/FoxO/Bim cascade [4], and resveratrol induces apoptosis of prostate cancer xenografts by inhibition of phosphorylation of FoxOs [5].