In nude mice, resveratrol inhibits orthotopic pancreatic tumors by PI3K/AKT pathway [3], capsaicin suppresses pancreatic tumor xenografts by JNK/FoxO/Bim cascade [4], and resveratrol induces apoptosis of prostate cancer xenografts by inhibition of phosphorylation of FoxOs [5]. The gene discussed is MAPK8; the disease is pancreatic neoplasm.