CASP3 and neoplasm: Pasireotide, octreotide, or everolimus, alone or in combination, did not induce apoptosis in the tested tumor samples as demonstrated by terminal deoxynucleotidyl transferase-mediated nick end labeling (TUNEL) assay or by the determination of caspase-3 and -7 activities (Supplementary Figure 1; for tumor characteristics, see Supplementary Table 2).