TPM3 and colorectal carcinoma: Although many different NTRK1 rearrangements have been already identified in a wide range of solid tumors (see www.ntrkfusions.com), only a limited number of fusion partners has been detected so far in CRC (TPM3-NTRK1, LMNA-NTRK1 and TPR-NTRK1 fusion genes) [5, 7, 8].