As presented in Figure 8A, there were 57 up-regulated genes common to the tumors induced by rb1 somatic inactivation (zebrafish tumors) and human medulloblastomas and PNETs most of which were involved in cell cycle progression and mitosis (such as cdk1, aurka, plk1, etc., Supplementary Table 3). This evidence concerns the gene AURKA and medulloblastoma.