However, 72 h after acute KIR, blood creatinine and BUN levels that indicate renal dysfunction, and the urine protein to creatinine ratio that indicate glomerular damage were lowest in the SC-F344 and SC-DPP4D rats and gradually increased in BIR-KIR-F344, KIR-DPP4D, DPP4D-KIR- exendin-9-39 rats and were highest in KIR-F344 rats (Figure 1). Here, KCNJ11 is linked to Abnormal renal physiology.