Among them CXCL12 rs1065297 and rs10793538 decreased CAD risk (rs1065297: OR=0.64, 95%CI: 0.46-0.90, p=0.010; rs10793538: OR=0.67, 95%CI: 0.47-0.93, p=0.016). The gene discussed is CXCL12; the disease is coronary artery disorder.