In our study, we show that EAM not only induced increase in Bax/Bcl-2 and protein expression level of cleaved caspase-3, but also induced up-regulation of the death receptors Fas mRNA level, suggesting that both intrinsic and extrinsic apoptotic pathways are involved in the pathogenesis of myocarditis. The gene discussed is FAS; the disease is myocarditis.