These antigens are attractive therapeutic targets, as PKD2 is dysregulated in several solid tumours, implicated in the transformation process, and a target for chemotherapy [16]; LSP-1 is a marker of lymphoma [17], and the RQA_V epitope is elevated on the surface of a range of tumour cell lines and primary leukemic tissue [11]; finally AMPD2 expression has been noted on both melanoma and ovarian carcinoma cell lines [5]. This evidence concerns the gene PKD2 and melanoma.