Similar results were observed in both types of bacterial infection; the mRNA expression of Snx10 in BMDMs was significantly upregulated after infection with heat-killed L. monocytogenes (HKLM), heat-killed E. coli (HKEC) and heat-killed S. typhimurium (HKST) but SNX10 upregulation after infection with VSV(vesicular stomatitis virus) was negligible (Figure 1D). The gene discussed is SNX10; the disease is bacterial infectious disease.