Dendritic cells (DCs) loaded with two LM immunodominant peptides, peptide 91-99 of listeriolysin O virulence factor, LLO91-99 and peptide 1-22 of glyceraldehyde-3-phosphate dehydrogenase (Lmo2459), GAPDH1-22 [10–12] or phagosomes obtained from macrophages and containing live wild type LM (LMWT) [13], prevented systemic listeriosis in mice. Here, GAPDH is linked to listeriosis.