The protein from A431 cells migrated at  ̃24-25 kDa when probed with the C-term antibody, a gel mobility similar to the protein from the non-CJD and sCJD brains when probed with antibodies pAb and N-20 (Figure 6), suggesting that it is the full-length caveolin-1 that should contain the C-term antibody epitope region. This evidence concerns the gene CAV1 and Creutzfeldt Jacob disease.