Canonical pathway analysis revealed (P < 0.001) that the top 7 pathways were the following: axonal guidance signaling (26 genes), role of NFAT in cardiac hypertrophy (16 genes), P2Y purigenic receptor signaling pathway (13 genes), cardiac hypertrophy signaling (17 genes), Tec kinase signaling (14 genes), ErbB signaling (10 genes), and CXCR4 signaling (13 genes) (Table 1). The gene discussed is EGFR; the disease is cardiac hypertrophy.