GAST and gastric cancer: Interestingly, we observed an increase in putative intracellular forms of CLU (60 and 75 kDa precursors of sCLU) in gastric cancer cells in response to gastrin and/or cisplatin, but without further comprehensive analyses, we do not know whether these peptides are exclusively located in the ER-Golgi-pathway, waiting to be secreted, or also locate to the cytoplasm, possibly interacting with mitochondrial and apoptosis-related proteins.