Many studies have shown that MHC class II expression is upregulated in SG epithelial cells from SS patients compared to healthy controls, while a role for IFN-γ in increased expression of antigen-presenting molecules [6, 7] and ICAM1 [8] on SG acinar cell plasma membranes and induction of antigen presentation is supported [9]. The gene discussed is IFNG; the disease is synovial sarcoma.