However, more evidence of an association between GST genotypes and AML was revealed during a pooled analysis of 29 studies, suggesting that the GSTM1-null genotype associates with an increased risk of AML in East Asians (p = 0.01; OR = 1.22; 95% CI 1.05–1.42), and GSTT1-null genotype in Caucasians (p<0.0001; OR = 1.48; 95% CI 1.29–1.69). The gene discussed is GSTM1; the disease is acute myeloid leukemia.