Phosphorylated Akt (p-Akt), also known as protein kinase B, is associated with multiple cellular processes by affecting cell proliferation and programmed cell death, etc. Research showed that an increased expression of p-Akt was involved in pulmonary fibrosis and could contribute to fibrogenesis, which was showed as the most significant factor associated with increased p-Akt expression by multivariate logistic repression analysis[19, 20]. Here, AKT1 is linked to pulmonary fibrosis.