Importantly, the single animal in the ZIKV + 5A3 treatment group at day 10 post-infection that showed no appreciable Iba-1 labeling by IR imaging was the same animal that at day 10 PI showed no detectable virus in the brain (Fig. 1b) and no significant whole-brain [18F]DPA-714 binding over controls (Fig. 2a, b). The gene discussed is AIF1; the disease is infection.