STAT6 and asthma: In a dual T-helper 2/T-helper 17 (Th2/Th17) model of steroid-resistant asthma, IL-13-mediated and signal transducer and activator of transcription 6 (STAT6)-dependent airway hyper-responsiveness (AHR) and mucus metaplasia was observed, however, IL-13 was not identified to be directly contributing to airway/tissue inflammation.