XIAP-deficient cells exhibited comparable results with a significantly reduced tumour volume (Ctrl: 590.8 ± 220.7 mm3 vs. XIAP KD: 107.9 ± 101.8 mm3; p < 0.01) and weight (Ctrl: 0.26 ± 0.11 g vs. XIAP KD: 0.048 ± 0.064 g; p < 0.01; Fig. 2F). This evidence concerns the gene XIAP and neoplasm.