FGFR1 and cardiac hypertrophy: To obtain further insight into potential FGFR-mediated signalling mechanisms in TAC-induced cardiac hypertrophy, we investigated mRNA expression of Fgfr1, Fgfr3 and Fgfr4 in WT, VDRΔ/Δ, Fgf23−/−/VDRΔ/Δ, and Klotho−/−/VDRΔ/Δ mice, 4 weeks after TAC.