AKT1 and schizophrenia: Total AKT protein was similar between schizophrenia and control (t = 0.82; df = 12; p = 0.43) (Fig. 4a), however phospho-AKT was decreased in schizophrenia subjects (t = 2.34; df = 12; p = 0.038) (Fig. 4b and Supplementary Fig. S2).