APOE and neuromuscular disease caused by qualitative or quantitative defects of dystrophin: The increase in Evan’s blue dye leak from the vasculature in mdx and mdx-ApoE mice supports the idea that there is inherent vascular dysfunction associated with dystrophin-deficiency and that, in the context of hyperlipidemia, this may facilitate circulating lipids to infiltrate the muscle tissue and to cause muscle damage or affect muscle repair and remodeling.