NFE2L2 and hepatocellular carcinoma: Subsequent ChIP-Seq analyses of Nrf2 binding sites in human lymphoblastoid cells treated with the dietary isothiocyanate sulforaphane (SFN) and in the mouse hepatoma cell line Hepa1c1c7 treated with the electrophilic agent diethyl maleate (DEM) showed preferential binding of Nrf2-sMaf heterodimer to 5′-TGACTCAGC-3′ (23, 52).