MAPK8 and neoplasm: In fact, in line with the opposite effect of MG-132 on the parasite compared with tumor cells, the S. mansoni p38 kinase (Smp_133020) and JNK1 (Smp_172240) gene homologs were detected here as expressed, however not significantly affected by MG-132, thus reinforcing the finding that apoptosis might not be induced, but rather diminished in the treated parasite.