POMC and growth hormone-producing pituitary gland neoplasm: In explaining discrepancies, we have to account that 85% of somatotropinomas are macroadenomas; it is possible that microtumors could still respond to glucose, similar to what happens in other endocrine adenomas (parathyroid adenomas responding to calcium or adrenocorticotropic hormone producing tumors responding to high doses of dexamethasone).