At the end of thirty days, serum levels of IL-6 and IL-8 were significantly higher in the COPD group compared to the control group (p < 0.05), while those in the resveratrol group were significantly lower than those in the COPD group (p < 0.05, Figure 3A,B). This evidence concerns the gene CXCL8 and chronic obstructive pulmonary disease.