We aimed to assess hepatic proteins in rheumatoid arthritis patient’s: inflammation markers (high-sensitive C-reactive protein (CRPhs), haptoglobin (Hp)), and those implicated in iron metabolism (ferritin, Albumin (Alb), Cp, α-1-acid glycoprotein (AAG) and Tf) and MPO. This evidence concerns the gene HP and rheumatoid arthritis.