Berry supplementation in the form of juice, powder, or extract has been shown to decrease serum levels of interleukin- (IL-) 12, monocyte expression of monocyte-to-macrophage differentiation-associated (MMD) and C-C motif chemokine receptor 2 (CCR2), and the overall inflammation score [98] and to improve endothelial function measured by the reactive hyperemia index [99] in MetS patients. Here, CCR2 is linked to metabolic syndrome.