We detected expression of γH2AX (Fig. 6C), the specific ATM target phospho-Kap16, 7 (Fig. 6D), and the p53 target p21 (Fig. 6E), in small ductal lesions – and to a lesser extent in mPanINs – in pancreatic tissues of 2-months old KC mice. This evidence concerns the gene ATM and keratoconus.