WT and Nfatc1−/− CTLs generated from CD8+ T cells of C57/BL6 mice by co-culture with irradiated Balb/c splenocytes for 6 d and A20J tumor cells as targets (see Supplementary Fig. 3b) revealed a 40% decrease in killing, compared to WT CTLs. This evidence concerns the gene NFATC1 and neoplasm.