Several studies investigated the role of TMEM16A in cancer cell proliferation using TMEM16A specific inhibitors such as CaCCinh-A01 and T16inh-A01, which inhibits TMEM16A currents [108, 109], and found that pharmacological inhibition of TMEM16A reduced cell proliferation in TMEM16A-overexpressing cancer cells [42, 71, 109, 110]. This evidence concerns the gene ANO1 and cancer.