ANO1 and head and neck squamous cell carcinoma: To exclude this possibility, Wanitchakool et al. compared the effect of siRNA-knockdown of TMEM16A on proliferation of HNSCC (BHY and CAL33) cells and colonic epithelial (HT29) cells, and found that TMEM16A knockdown suppressed proliferation in HNSCC cells, but not in HT29 cells [59].