To evaluate the associations of TCM constitutional types with insulin resistance, we compared serum levels of IL-6, TNF-α, adiponectin, leptin, GLP-1 and GIP in patient subgroups dividing by the presence of TCM constitutional types, including Qi-deficiency constitution, Phlegm-damp constitution and Damp-heat constitution. The gene discussed is GCG; the disease is Insulin resistance.