Birgitt Schüle, at the Parkinson’s Institute and Clinical Center in Sunnyvale, California, and colleagues examined the clinical features of seven family members in a Mexican family and used the latest genetic technologies to analyze their repeat expansions in ATXN10. Those that experienced hallmark symptoms of spinocerebellar ataxia, such as problems with coordination and seizures, were found to carry interrupting sequences within the ATXN10 repeat expansion. The gene discussed is ATXN10; the disease is cerebellar ataxia.