Thus, the increased likelihood of poor prognostic factors among MELF-positive cases in our cohort emphasizes the implications of accurate histologic assessment of myometrial invasion and recognition of MELF pattern invasion in clinical practice in terms of grading of EEAs, and assessing long-term prognosis given its association with LVSI, lymph node metastasis, and extra-uterine disease (4, 5, 7, 8, 10, 14). Here, EPM2A is linked to Lafora disease.