SH2D1A and helminthiasis: In addition, and contrary to previous observations in immunization studies, and virus and helminth infections (Crotty et al., 2003; Cannons et al., 2006; Kamperschroer et al., 2006; Crotty et al., 2006; McCausland et al., 2007; Moyron-Quiroz et al., 2009; Yusuf et al., 2010; Morra et al., 2005), we show that SAP-deficient mice are able to activate Tfh and GC B cells, and an IgG response to the parasite.