However, a technique more sensitive to detect parasitemia, i.e. transfer of 100 μl of blood from Sh2d1a−/− and wt mice at this time into Rag2−/− mice, demonstrated that 50% of these Sh2d1a−/− mice were still sub-patently infected, whereas confirming that all wt C57BL/6 mice had cleared their infection (Table 1). This evidence concerns the gene RAG2 and parasitic infectious disease.