MIER3 and metastatic malignant neoplasm in the lymph nodes: As summarized in Table 1, the expression of MIER3 was significantly associated with differentiation (p = 0.038), clinical stage (p = 0.035), T classification (p = 0.029), lymph node metastasis (p = 0.029), and distant metastasis (p = 0.022) in patients with CRC.