In OVA-treated WT mice, PM2.5 exacerbated OVA-related lung eosinophilia along with an increase in Th2 cytokines (IL-5, and IL-13) and chemokines (eotaxin and MCP-3) and infiltration of eosinophils into the airways. This evidence concerns the gene IL5 and Increased total eosinophil count.