Univariable analysis demonstrated that large tumor size (p<0.0001), lymph node metastasis-positivity (p = 0.0492), nuclear grade 3 (p<0.0001), ER-negativity (p = 0.0006), PgR-negativity (p = 0.0014), high levels of Ki67 (p<0.0001), pS6-positivity (p = 0.0045), pMAPK (p = 0.0174), TP53 (p = 0.0048) and high levels of geminin (p<0.0001) were significantly associated with high levels of SUVmax (Table 2). Here, ESR1 is linked to metastatic malignant neoplasm in the lymph nodes.