CASP3 and neoplasm: To complement the above data showing an anti-metastatic effect of Foxy-5 in animals inoculated with DU145-Luc cells, we stained their primary tumors, RLN and DLN with specific antibodies to identify tumor cells (human-vimentin staining), apoptotic cells (cleaved-caspase 3 staining) or actively proliferating cells (Ki67 staining).