Thus, many genes involved in PPAR‐targeted functions were regulated, including lipid metabolism (CIDEA, SCD, and Fabp3), chronic kidney disease (FGF23), ion transport (Atp2a1 and Atp1a2), mitochondrial oxidative phosphorylation (Cox8b), stress response (Gpx3), inflammation (IL‐10 and IL‐1β), immunity (TLR2‐9 and NODR1‐2), and water channel (AQP3‐5). The gene discussed is ATP1A2; the disease is chronic kidney disease.