Peroxisome proliferator-activated receptors (PPARs) comprised of three different isoforms, namely, PPARα, PPARβ, and PPARγ, play a vital role in the biological processes of the metabolic syndrome, including fat generation, lipid balance regulation, energy metabolism, insulin sensitivity, cell differentiation, and immune response [11,12,13,14]. The gene discussed is PPARA; the disease is metabolic syndrome.