ATF6 staining was generally strong in the neoplastic lesions: the median ATF6-IHC score in 43 samples of neoplasia was 6.0 (range, 2–11), which was significantly higher (p < 0.001) than that in 93 samples without neoplasia (median, 3.0, range, 0–11). Here, ATF6 is linked to neoplasm.