For example, miR-219-5p inhibited the growth and metastasis of gastric cancer cells via targeting LRH-1 [17], and miR-219-5p exerted a antitumor function in colon cancer via binding to Sall4 [12]; however, the expression and effect of miR-219-5p in melanoma still remained unclear. Here, SALL4 is linked to colonic neoplasm.