We targeted two types of cancer cells natively expressing high levels of CD47 and tumor-specific antigens (TSAs), viz., Toledo, a human non-Hodgkin’s lymphoma cell line representing hematologic cancer that expresses CD20, and DLD1, a human colon cancer cell line representing non-hematopoietic solid tumor that expresses EGFR (Supplementary Fig. 10). Here, CD47 is linked to colonic neoplasm.