SRRM2 and cancer: The distinct phosphoprylation profiles of SRRM2 may indicate its different catalytic preference and the way interacting with other SR proteins in three cell lines57–59 To predict upstream kinases targeting 31 differential phosphoproteins form cancer driver genes (Table S7), we used Kinase-specific Phosphorylation Site Prediction (GPS) service and found 41 high-confident kinases candidates.