Thus, it remains to be determined if our finding of high expression of combined FUT1 and B3GALT5 as an independent risk factor for postoperative recurrence and OS in patients with resectable HCC will apply to HCC patients from different ethnicities or different etiologies, such as alcoholic and nonalcoholic steatohepatitis. Here, B3GALT5 is linked to metabolic dysfunction-associated steatohepatitis.